"Conclusion. These results indicate that in early AMD Saffron supplementation induces macular function improvements from baseline that are extended over a long-term followup."
"Age-related macular degeneration (AMD) is a retinal neurodegenerative disease whose distinctive features in the early stage are large soft drusen and hyper/hypopigmentation of the retinal pigment epithelium (RPE), with a moderate loss of central vision (age-related maculopathy, following the International Classification, ). In its late stage, the disease is characterized by the geographic atrophy of the RPE or the subretinal neovascular membranes, leading to a more severe central visual impairment which is a major cause of severe, irreversible low-vision in elderly people of developed world."
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