
rheumatologist Dr. Robert Bunnin, of the National Rehabilitation Hospital in Washington, DC:
"The drugs are supposed to work by shutting down the cells that re-absorb the bone, the osteoclasts. The ones that make the bone, the osteoblasts, are supposed to keep working. However in biopsies of patients who have had the fracture, it shows that both are shut down."
Image left: Double the bone with double the risk of fracture
Bunning calls it "frozen bone," which is brittle and more susceptible to these types of clean fractures. He says in the U.S. There have been 50 to 60 reported cases of this.
"Even thought it’s rare, I think we’re going to be seeing quite a few more cases."
Dr. Bunning says that in all of the reported cases, most patients had been taking Fosamax or another type of bisphosphonate for more than 5 years.
