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Showing posts with label rheumatoid arthritis. Show all posts
Showing posts with label rheumatoid arthritis. Show all posts

Monday, November 17, 2014

Is Low Dose Naltrexone (LDN) really the cure-all for autoimmune diseases?

One of my clients sent me a copy of this email broadcast from a well known paleo advocate and holistic practitioner, Chris Kresser:


"Those of you who’ve been following my work for some time may know that my wife Elanne and I struggled to conceive for almost two years after we first decided to start a family. During that process we discovered that Elanne was suffering from autoimmune hyperthyroidism (i.e. Graves’ disease).


The endocrinologist we saw wanted to put her on PTU, a toxic drug that suppresses thyroid function. Not surprisingly, neither of us were in favor of that, so I did what I do in these situations—I read everything I could get my hands on in the scientific literature about Graves’, autoimmunity, and emerging treatments.



One of the treatments I came across was low-dose naltrexone (LDN). And after researching it thoroughly, and talking with some physicians who had experience working with it, both Elanne and I were convinced that it was worth a try.



In just two months after starting LDN (along with some other supportive changes), there were no signs that Elanne had ever suffered from hyperthyroidism. And about a month after that, Elanne was pregnant with our daughter Sylvie.



Today, Sylvie is 3.5 years old and one of the healthiest and most vibrant kids I’ve ever met. Elanne is still taking LDN, and is still completely free of hyperthyroid symptoms. She never had to take PTU or other toxic drugs, and unlike many hyperthyroid patients, she didn't have to have her thyroid gland surgically removed.



Since then I have seen LDN work similar miracles in many of my patients with autoimmune diseases ranging from rheumatoid arthritis, to Crohn’s disease, to Hashimoto’s. It’s not a panacea, and it doesn’t work for everyone, but when it works it is extremely effective (not to mention safe and well-tolerated)."



Very interesting, especially when coming from a "Holistic Practitioner"!

I've been reading about Low Dose Naltrexone (LDN) for a few years; but am not keen on it despite some well known authorities advocating it.  

The problem I have is it merely suppresses the symptoms of disease and therefore lulls a person into a false sense of security while the disease continues to percolate away, now unseen.  Its a bit like rust in the chassis of your car, or rot in your house: you can't see it, but it is there quietly doing irreparable damage.  Merely painting over the visible expressions of the rust or rot does not get rid of the problem.

The absence of symptoms does not necessarily mean the absence of disease


I am interested in identifying and dealing with the ROOT CAUSES of disease and not being distracted with chasing symptoms.  Treating symptoms with a drug is easy while finding and dealing with root causes can be expensive and frustrating.  But the rewards are amazing when eventually discovered and remedied - and worth every cent and every minute:

Autoimmune conditions such as Crohn's, Hashimoto's and rheumatoid arthritis are symptoms of something being seriously amiss deep within the body.  These are not diseases caused by a deficiency in Naltrexone.  There is something fundamental at play.  For example; there is a close link between rheumatoid inflammations and chronic, subclinical infection that may have been going on for years and years.  The same goes with Hashimoto's or Graves.  Have you ever wondered what causes all of those terrible ulcerations in the gut of a person suffering Crohn's or similar diseases of the digestive tract?  Infection, including parasites?  Then there are chronic nutritional deficiencies such as the lack zinc and selenium, sometimes complicated by the presence of heavy metals such as mercury and lead.  Problems with zinc and selenium result in poor healing, inflammation and ulcerations.  Most people are iodine deficient and iodine is essential for health, including the thyroid.  

One of the consequences of chronic physical, infectious or psychological stress is immune dysfunction and the adrenals and thyroid are right in the firing line.  With the eventual onset of adrenal and thyroid exhaustion, the body may flick into a desperate state of hyperthyroidism, as if desperately making a final lunge for the finish line.  And have you ever wondered why autoimmune conditions are much more prevalent in women than men?  That's all to do with hormones.  Contraceptives and HRT can throw a woman's hormones into complete disarray.  

Naltrexone, or any other drug, for that matter, will not "cure" any of these root causes and may actually make matters worse over the long term.  

All drugs, low dose or high dose, come with long lists of nasty side effects.  The longer one is on the drugs, the greater the odds are that one or more of these side effects will be expressed.  Once expressed, getting better may be all the more difficult.  

Don't get me wrong - I'm not all against drug use - Drugs - yes - in certain cases and with due care and judicious application.  

While it may be necessary to take a drug to rescue an acute or intolerable situation, the search for and elimination of the root causes of the distress remains all important, if not even more so.

Health Warning! 

Non drugs remedies that are directed at root causes have two major side effects - Looking good and feeling great!

Cheers!



About this website 
The advice in these articles is given freely without promise or obligation. Its all about giving you and your family the tools and information to take control of your health and fitness.
Candida and Fungal Infections? Gary Moller recommends you explore this programme: Click Here!

Monday, October 13, 2014

Exciting news about tocotrienols, inflammatory diseases cardiovascular health

 2011;17(21):2147-54.

Tocotrienols and cardiovascular health.

Abstract

This review emphasizes the effects of tocotrienols on the risk factors for atherosclerosis, plaque instability and thrombogenesis, and compares these effects with tocopherol. Tocotrienols reduce serum lipids and raise serum HDL-C. Alpha-tocopherol, on the other hand, has no effect on serum lipids. Tocotrienols have greater antioxidant activity than tocopherols. Both reduce the serum levels of C-reactive protein (CRP) and advanced glycation end products, and expression of cell adhesion molecules. The CRP-lowering effects of tocotrienols are greater than tocopherol. Tocotrienols reduce inflammatory mediators, δ-tocotrienol being more potent, followed by γ- and α-tocotrienol. Tocotrienols are antithrombotic and suppress the expression of matrix metalloproteinases. They suppress, regress and slow the progression of atherosclerosis, while tocopherol only suppresses, and has no effect on regression and slowing of progression of atherosclerosis. Tocotrienol reduces risk factors for destabilization of atherosclerotic plaques. There are no firm data to suggest that tocotrienols are effective in reducing the risk of cardiac events in established ischemic heart disease. Alpha-tocopherol is effective in primary prevention of coronary artery disease (CAD), but has no conclusive evidence that it has beneficial effects in patients with established ischemic heart disease. Tocotrienols are effective in reducing ischemia-reperfusion cardiac injury in experimental animals and has the potential to be used in patients undergoing angioplasty, stent implantation and aorto-coronary bypass surgery. In conclusion, experimental data suggest that tocotrienols have a potential for cardiovascular health, but long-term randomized clinical trials are needed to establish their efficacy in primary and secondary prevention of CAD.
PMID:
 
21774782
 
[PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/21774782
________________________________
Gary:
My interpretation is as follows:

CRP, as a measure of inflammation, is arguably a better predictor of cardiovascular risk than cholesterol.  You will note that tocotrienols also reduce glycation which is exciting news for diabetics.  Glycation is also one of the best indicators of the decrement in cellular health associated with ageing.

Tocotrienols may be beneficial for other inflammatory diseases like rheumatoid arthritis and, I suspect, diseases such as multiple sclerosis.

Tocotrienols reduce the risk of blood clots such as seen in cases of deep vein thrombosis and reduce and may even reverse the formation of artherosclrotic plague that can lead to heart attack, stroke, poor eyesight and dementia.

Tocotrienols may reduce ischemia-perfusion cardiac injury - better known as angina and the damage it may cause to heart muscle.

They may be a safe alternative to drugs like aspirin and warfarin.

Tocotrienols are more effective for the above as compared to vitamin E.

As per usual, no researcher is ever going to finish their conclusions without recommending more research.  Got to keep the funding coming in to keep employed.  That's fine - we need much more research about nutrition alternatives to expensive and harmful pharmaceutical drugs; but that does not mean we sit on our hands and wait and wait and wait....

Incidentally, I am not aware of any side effects from taking these other than looking good and feeling great!

Conclusion:

If you are one of the 80% of the population who are at risk of suffering cardiovascular-related ailments during your life time, it makes sense to include tocotrienols in your daily diet.

Please contact me if you are interested in learning more about tocotrienols and whether this may be beneficial for you.  If you have a health condition and on medication then you must arrange a consultation before making any changes or adding a supplement such as these:
http://www.garymoller.com/Consultation/Private-Consultation.aspx

More related articles:










About this website 
The advice in these articles is given freely without promise or obligation. Its all about giving you and your family the tools and information to take control of your health and fitness.
Candida and Fungal Infections? Gary Moller recommends you explore this programme: Click Here!

Wednesday, December 04, 2013

Do you know about Minocycline therapy for arthritis? (updated 4/12/2013)

Hello Gary,
I wrote you about 18 months ago or so regarding a back injury and purchased your book.
Prior to that I was dealing with Palindromic Rheumatism and osteoarthritis for 12 years, I am now 57 years of age.

Several different doctors diagnosed my back injury as herniated disks - yet the rheumatologist and surgeon disagreed and said that my back was full of arthritis.

Wednesday, June 20, 2012

Is my wife's rheumatism inherited - in her genes?



High HTA Ca associated with arthritis & osteoporosis.
Low HTA NA & K associated with steroid use.
Low HTA Cu associated with rheumatoid arthritis.
High HTA Zn associated with viral infections.
(HTA = Hair tissue analysis)
"Hi Gary,
I am writing this email to ask for a favour in the name of my wife. She has got some health problems for a year or two now.  

She had knee surgery to remove meniscus of one of her knees and another surgery to fix the meniscus in the other one. It has been over a year since the surgery took place but both knees are still painful.

She has also been having frequent and reacquiring ear infections recently, which do not healed despite using ear drops with antibiotics.

Last blood test has reviled that her ASL is way over the limit. She has 323 and the limit is 200 (a copy of it attached to this email). Her doctor is linking it all to some kind of virus that the blood test indicates, and suggested a use of antibiotic ks orally this time.

Now, my wife is very much into natural medicine so she wants go for colloidal silver instead of the antibiotics ( she is on it for a week now) but at the same time she is a little worried about the whole thing specially because her mom has been suffering from rheumatism for years and despite using cortisone and some other steroids, her health decreased a great deal and she is in a very serious state now. 

Cutting the long story short it is all about genetics thinks my Dr.

Now what you think she should do? Can you give us an advise pleas, we would really appreciate it!!

Thanks
p.s. Unfortunately she is as smoker as well, and it does not help for sure."
(Name withheld).
_____________________________________
Gary:
Is it genetic, or is it hereditary?  In my opinion, while there may be a genetic component, which is part of "heredity", the main driver behind the mix of ailments your mother-in-law and wife are dealing with are all mostly of the controllable inherited kind.

When your wife was first conceived all her nutrients and hormones came from her mother.  When she was born, she would have had all the biochemical deficiencies and excesses of her mother.  Then she was presumably breastfed by her mother and then ate the same food as the family for the following 20 years and shared any family stresses and strains.  So, it is hardly surprising that a Mother's health trends are passed onto her children.  By contrast, there is a weaker association between father and children.

Even if a health problem has a strong genetic component, the question must be asked as to why a particular gene is switched on or off in one sibling but not in the others?  There maybe a controllable factor such as a nutrient imbalance or environmental toxin.  Having said this, once a gene is switched, such as the one that turns hair grey, it may be impossible to switch it the other way.

In your wife's case, she displays many of the characteristics of a woman with thyroid and adrenal issues with associated nutrient imbalances, such as those portrayed in the Hair Analysis Chart above.

When a copper deficiency is present, iron may build up in the soft tissues, including the cartilages.  This contributes to inflammation and degradation of the joints.  A chronic bacterial infection can contribute to this process.  This is why rheumatoid arthritis can develop following an infectious disease.

Elements such as mercury, cadmium, zinc and lead are antagonists to copper.  Some of these are found in tobacco smoke, amalagum fillings, fish such as tuna and from industrial pollution.

Low levels of zinc in the tissues will predispose a person to recurring viral, yeast (candida) and fungal infections.

When low and/or in imbalance with copper, there is an association with collagen disorders, most commonly seen as stretch marks of the skin.  The same disorder is associated with ligament, tendon and cartilage injuries - often spontaneous and without violence.

Copper and zinc regulate oestrogen and progesterone.  When copper rises, so does oestrogen.  When zinc rises, so does progesterone.  Therefore, imbalances between copper and zinc are closely associated with menstrual and conception disorders.

The role of zinc and copper and the production of the female hormones explains why conditions like collagen disorders, joint injury, stretch marks, viral, yeast and fungal infections and rheumatoid arthritis are far more common in women than in men.  When collagen is weak there will be easy bruising and susceptibility to gum disease.  Gum disease, when combined with smoking may be all that is required to set of rheumatic pains.

Oestrogen and progesterone contraceptives, especially the long term implants and IUDs may be especially damaging to a woman's health due to their messing up of a woman's copper and zinc balance.

With regards to your wife, I can appreciate your deep concern for her immediate and long term health.  However; I am reluctant to offer specific advice without her first doing a Hair Tissue Analysis.  This is because there could be a number of things going on.  For example; she may have exceptionally high copper which can give the same symptoms as a deficiency.  We need to know if this is, or isn't the case before we start pumping her full of copper.

So, my advice is to get a Hair Tissue Analysis done asap and then we will act according to the finding.

In finishing, thank you for raising this issue.  It is a pressing one that I am encountering almost daily.  Merely drugging these women with anti-inflammatories and steroids is not the solution.  While such therapies may give relief, it is only temporary and the consequences can be huge such as drugs dependency, chronic arthritis, osteoporosis, chronic fatigue and depression.  The solution lies in identifying the underlying causes and then setting about correcting these by lifestyle and nutrition.



_______________________________________
About this website
The advice in these articles is given freely without promise or obligation.  Its all about giving you and your family the tools and information to take control of your health and fitness.

Monday, July 02, 2007

Advice about Palindromic Rheumatism

Gary,
I was diagnosed 10 years ago with something called "Pallindromic Rheumatism" then I had a sports injury (flipped off my bike into a ditch) and had Fibromyalgia - the FM is completely gone - also I have as anyone would at my age 55 osteoarthritis. There never seems to be a definitive diagnosis in my mind - thats when 7 years ago I returned all the prescriptions to the Doc and went organic with supplements.

I take Calcium, a good multi, vitamin C with E and mix in a little baking soda to keep me alkaline, milk thistle when I'm on Robaxacet, niacin, super B's, probiotics and fish oil. I also stay totally away from anything that is processed. I juice at least every other day and basically start my day like no one else on the planet by eating vedge and fruit and I drink gallons of pure water.
The Pall R. migrates from major joint to major joint. The osteo affects both hips and spine, cervical, thoracic and lumbar....I do take something we have here called Robaxacet with a muscle relaxant that has helped me through a few hurdles. My biggest drug has always been exercise, and I'm very cognizant of not over doing, but movement is essential and my first drug of choice. I have started Bromelain which seems to help. Unfortunately they do not know what is causing the current problems (and frankly I don't expect them too) but I am having an MRI in July. Today I warmed up on the treadmill (slowly) did 30 minutes and then lifted light weights for a couple of sets.
All of the above started after consuming bad well water for 3 months just over 10 years ago - seemed to be a catalyst for the arthritis and it was at that time that I was diagnosed with hypothryoidism. BUT, a few years back I discovered that there were many foods that seemed to put me into a flare up i.e, salt, soya, peanuts etc......hence my organic and only fresh foods. I
also no longer clean with chemicals - it's all quite an amazing journey. I swam for a while but have some problems with chlorine so I wait for the warm weather and jump into any lake I can find.
______________________________________
Gary Moller comments:

Please view the video commentary for rheumatoid arthritis along with these notes:
  • Palindromic rheumatism is closely linked with rheumatoid arthritis. Read this.
  • The osteoarthritis and the allergies may have similar underlying causes - a dysfunctional immune system.
  • Fibromyalgia is related to mineral depletion and low vitamin D.
  • The hypothyroidism may be similarly linked.
  • Low vitamin D is a likely factor as is trace mineral depletion and deficiency in the fat soluble vitamins (A, D, E and K).
  • All of these are essential for a robust immune system, strong bones, healthy joints and healthy metabolism (thyroid function).
  • Drinking pure water flushes the body of minerals and water soluble vitamins. It may interfere with digestion by diluting the digestive acids and enzymes.
  • Baking soda may interfere with digestion by neutralising the digestive acids.
  • Acidity in the digestive processes is also important for uptake of minerals.
  • A low fat diet that is also low in animal products, including organs like the liver, will not supply sufficient minerals or fat soluble vitamins.
  • Multi vitamins and other supplements of synthetic origins, may not be as effective or as safe as natural ones that are rich with nutrient co-factors.


Recommendations:
  • Get a blood test asap to assess vitamin D status.
  • If less than 120nmol, take measures to boost it urgently (Free range egg yolk, organ meat from free range sources, raw grass fed full fat dairy products, fish head broth, beef bone broth, cod liver oil, natural vitamin D supplements (available from http://www.myotec.co.nz/ ).
  • During winter take 2-4,000 iu supplementary Vit D per day, unless levels are already well over optimum.
  • When you take the fat soluble vitamins, you must include fat in the diet with them otherwise their uptake is seriously compromised.
  • Get a hair tissue mineral analysis right away. Details here.
  • Stop taking baking soda. The juicing etc is alkaline enough.
  • Take a quality mineral supplement right away in addition to the diet recommendations.
  • Only drink as much water as needed to ward off thirst and this should be a rich mineral water - stay away from distilled water.
  • Start taking daily glucosamine and chondroitin (Powder form is best value) from http://www.myotec.co.nz/ . This nutritional supplement is of proven benefit and is applicable to all forms of arthritis, including the inflammatory forms.
  • Take up to 2,000mg of vitamin C per day through diet and natural supplements. Vit C is important for immune health as well as for healthy joints and connective tissue.

Thursday, June 21, 2007

Which Joint food formulation is the best one for you?

In this video, I explain the differences between the three commonly available glucosamine and chondroiting joint food powder formulations.

Monday, May 07, 2007

Walking a marathon, rheumatoid arthritis and glucosamine

I would like to walk the Rotorua Marathon in 2008, and am trying to find some training advice. I notice that you have free on-line training for a marathon which just seems to be for runners, and I wonder if there is anything more specific for walkers.

I'm almost 62 and started walking when I gave up smoking some 6 years ago. At first I just did it to get fit, but then I started entering events - have done the Wellington Round the Bays a couple of times, and the Waitarere Great Forest walk most every year since 2002, initially just the 10 km event, but did my first half marathon in 2005. I've also done the Harbour Capital half marathon, and generally I've completed in under 3 hours, fastest one was around 2hr 53 min.

I had a bit of a set back towards the end of 2006 when I developed rheumatoid arthritis, and for a while I thought I would never be able to walk any distances again. However, it is now under control and I'm back out there again - did 10k Forest Walk last week in 1 hr 33 min so think I'm getting better again. I hope to do the Harbour Capital half marathon distance in June, and then would like to start thinking about doing a full marathon, and especially the Rotorua Marathon in April.

I don't belong to a club, and have used the training schedule on the Harbour Capital web site to prepare myself for doing the half marathons. However, I think I probably need a bit more help with training for a marathon, not just the schedule, but also some ideas about nutrition, and any tips that might help, both in building up fitness and during the event.

If you don't have specific training advice for walkers I wonder if you can point me in the direction of where I might find some.

....................... At the moment I'm taking methotrexate - 7 x 2.5mg tablets once a week, plus 1 folic acid 5mg tablet two day prior.



When my symptoms first started to appear, my doctor gave me synflex and referred me to the Rheumatology clinic at XXXXX. After quite a wait to get an appointment the doctor I saw there gave me diclofenac and referred me for more test (xrays, bloodtests) before he would make a diagnosis. In January when my symptoms had worsened to the extent that I could hardly walk due to pain in my feet and knees, and was also having difficulty with my hands, I finally went private and saw ......... He diagnosed rheumatoid arthritis and put me on a course of prednizone plus the methotrexate (5 x 2.5mg). The prednizone was like a miracle and within a fairly short time, the pain was gone and I was almost functioning normally again. I finished the prednizone around the 6th March and am now just on the methotrexate. When I saw Dr XXXX again early in April he felt that my arthritis was not as well controlled as he would like and so increased the methotrexate.

As far as any other medication is concerned, I took glucosamine tablets, and Omega 3 Fish Oil for a while, stopped the Glucosamine when Dr XXXXX didn't support it as being of any value, but continued with the fish oil which he said research supports as being beneficial for rheumatoid arthritis sufferers. I sometimes take Codalgin if I've been doing a bit much and find my feet or hands are a bit sore.



Once the pain was more under control I started back walking again, just taking it fairly easy, and also doing a bit of bike riding, as I found this was less stressful on my feet and legs. However, I have gradually increased my walking and have done two 10 km walks now - the Waitarere Forest walk on 31 March (where I managed the 10 kms in 1 hr 33 mins), and the Moonshine Walk on 15 April (did this 10 km in 1 hr 26 mins). I try and walk two or three times a week, using some of the training programes that I've found on the Harbour Capital Marathon web site, and am thinking of building up my training again to do their 1/2 marathon in June.

Dr XXXX has said increasing my walking again is fine as long as I don't overdo it, and ease up if I get more pain at any time. And so, I'm still keen to try and do a full marathon, and this was what led me to contacting you after I found your training for runners, when I was looking for some infromation about walking training for walking on the Rotorua Marathon web site.

I still intend to go and see my GP Dr XXXXX to see about getting my vitamin D levels checked as you recommended, and will let you know the results of this.

Regards
"C"